Researchers have developed a next-generation bionic hand that allows amputees to regain their proprioception. The results of the study, which have been published in Science Robotics, are the culmination of ten years of robotics research.
The next-generation bionic hand, developed by researchers from EPFL, the Sant’Anna School of Advanced Studies in Pisa and the A. Gemelli University Polyclinic in Rome, enables amputees to regain a very subtle, close-to-natural sense of touch. The scientists managed to reproduce the feeling of proprioception, which is our brain’s capacity to instantly and accurately sense the position of our limbs during and after movement – even in the dark or with our eyes closed.
The new device allows patients to reach out for an object on a table and to ascertain an item’s consistency, shape, position and size without having to look at it. The prosthesis has been successfully tested on several patients and works by stimulating the nerves in the amputee’s stump. The nerves can then provide sensory feedback to the patients in real time – almost like they do in a natural hand.
The findings have been published in the journal Science Robotics. They are the result of ten years of scientific research coordinated by NCCR Professor Silvestro Micera, who teaches bioengineering at EPFL and the Sant’Anna School of Advanced Studies, and Paolo Maria Rossini, director of neuroscience at the A. Gemelli University Polyclinic in Rome. NCCR Robotics supported the research, together with the European Commission and the Bertarelli Foundation.
Current myoelectric prostheses allow amputees to regain voluntary motor control of their artificial limb by exploiting residual muscle function in the forearm. However, the lack of any sensory feedback means that patients have to rely heavily on visual cues. This can prevent them from feeling that their artificial limb is part of their body and make it more unnatural to use.
Recently, a number of research groups have managed to provide tactile feedback in amputees, leading to improved function and prosthesis embodiment. But this latest study has taken things one step further.
“Our study shows that sensory substitution based on intraneural stimulation can deliver both position feedback and tactile feedback simultaneously and in real time,” explains Micera. “The brain has no problem combining this information, and patients can process both types in real time with excellent results.”
Intraneural stimulation re-establishes the flow of external information using electric pulses sent by electrodes inserted directly into the amputee’s stump. Patients then have to undergo training to gradually learn how to translate those pulses into proprioceptive and tactile sensations.
This technique enabled two amputees to regain high proprioceptive acuity, with results comparable to those obtained in healthy subjects. The simultaneous delivery of position information and tactile feedback allowed the two amputees to determine the size and shape of four objects with a high level of accuracy (75.5%).
“These results show that amputees can effectively process tactile and position information received simultaneously via intraneural stimulation,” says Edoardo D’Anna, EPFL researcher and lead author of the study.
The technologies pioneered by this study will be further explored during the third and final phase of NCCR Robotics, which will run until 2022 with Micera leading the Wearable Robotics research programme. “During the next phase, we plan to expand the use of implanted systems for prosthetics and rehabilitation, and the implants we used in this experiment will be tested in combination with different wearable devices and for different applications” explains Micera.
E. D’Anna, G. Valle, A. Mazzoni, I. Strauss, F. Iberite, J. Patton, F. Petrini, S. Raspopovic, G. Granata, R. Di Iorio, M. Controzzi, C. Cipriani, T. Stieglitz, P. M. Rossini, and S. Micera, “A closed-loop hand prosthesis with simultaneous intraneural tactile and position feedback”, Science Robotics.